HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 1-(2-Acetoxyethyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 1H-Indole-1-ethanol | HCID 13734996 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-(2-Acetoxyethyl)indole | HCID 15163042 | — |
Reaction Steps
An ice-cooled solution of 4.6 g of 1-(2-hydroxyethyl)indole in 10 ml of diethyl ether was treated with 1 ml of pyridine and 4 ml of acetic anhydride. After 2 hours 50 ml of water were added, the mixture was extracted with 100 ml of dichloromethane and the dichloromethane extract was dried. The solvent was evaporated to give 5.7 g of 1-(2-acetoxyethyl)indole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE036736 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-8b6ea5fa07d9460a8b33480af20b625e |
| Source note | uspto-grants-2000_06 |