Potassium Hydroxide → HCID 18780378, compound

HRID 1421197Notes

Reaction equation

HRID 1421197 reaction equation
[OH-].[K+].[C:3]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]([O:30]CC)=[O:29])=[CH:13][CH:12]=2)=[CH:7][CH:6]=1)#[N:4]>C(O)C>[C:3]([C:5]1[CH:6]=[CH:7][C:8]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][C:28]([OH:30])=[O:29])=[CH:13][CH:12]=2)=[CH:9][CH:10]=1)#[N:4]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 18780377HCID 18780377, compound

Product 1

HCID 18780378HCID 18780378, compoundYield 74%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Ethanol solution with 1.4 g of potassium hydroxide dissolved therein was added to 7.7 g of ethyl 11-(4-cyanobiphenyl-4'-oxy)undecylate obtained in step 2. The mixture was reacted under reflux conditions for 24 hours to obtain 11-(4-cyanobiphenyl-4'-oxy)undecanoic acid which is the target compound. The yield was about 74%.

Workup

  1. customThe mixture was reacted under reflux conditions for 24 hours

Sources & evidence

ORD record
ord-14caf6d59c0844f6862491ca0cc3b33b
Source dataset
uspto-grants-2000_06
Patent number
US06074710

Reaction notes

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