HCID 70296521, compound → HCID 54028746, compound

Participants

Reaction Steps

1.2 g (3.56,mmoles) of 1-(4-aminostyryl)-4-methyl-7,8-dimethoxy-3,4-dihydro-5H-2,3-benzodiazepine prepared according to Example 33 is suspended in 6 ml of acetic anhydride. The suspension is stirred for 1 hour at room temperature. In the meantime the starting compound gets dissolved, the end-product begins to separate and the reaction mixture gets thick. The separated product is filtered off, washed three times with 15 ml each of diethyl ether and dried at a temperature between 80° C. and 100° C. Thus 1.07 g (71.3%) of the desired compound is obtained.

Provenance & Evidence