Hydrochloric Acid → HCID 15481612, compound

Participants

Reaction Steps

A solution of (S)-1-(5-acetoxyhexyl)-7-benzyl-3,8-dimethylxanthine (350 mg) in methanol (20 ml) was treated with 1 M hydrochloric acid in ether (2.5 ml) and stirred for 12 hours. After evaporation of volatiles under reduced pressure, the residue was dissolved in ethyl acetate (100 ml), washed with saturated aqueous sodium bicarbonate solution (30 ml), dried over magnesium sulfate and concentrated. Yield=270 mg.

Provenance & Evidence