HCID 18780615, compound → HCID 18780625, compound

Participants

Reaction Steps

A solution of 5-benzyloxy-2-(4-benzyloxyphenyl)pyrrolo[2,1,5-cd]indolizine (48 mg, 0.11 mmol) in 2 ml of tetrahydrofuran and 3 ml of ethanol was hydrogenated in the presence of 10% palladium on carbon (30 mg). When the theoretical amount of hydrogen had been consumed the catalyst was filtered off and the filtrate was evaporated to afford 27 mg (99%) of the title compound. M.p. 165° C. (dec.). 1H-NMR (DMSO-d6, 200 MHz) δ: 6.92 (d, 2H), 7.15 (d, 1H), 7.36 (d, 1H), 7.43 (s, 1H), 7.73 (d, 1H), 7.88 (d, 2H). (Compound 53).

Provenance & Evidence