HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → N-(2-hydroxyethyl)-aminobutyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | Crotonic Acid | HCID 637090 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(2-hydroxyethyl)-aminobutyric acid | HCID 18780751 | — |
Reaction Steps
A solution of 86 g of crotonic acid (1 mole) and ethanolamine (1 mole) in pyridine (200 ml) is refluxed for 2-3 hours and subsequently cooled. The resulting product is filtered and recrystallized to yield the title compound having m.p. 178-180° C. (Compound 1.1, Table 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06075051 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-b731145f17b94acfbc45469dfbb0a26a |
| Source note | uspto-grants-2000_06 |