Hydrogen Bromide → HCID 11132283, compound

Participants

Reaction Steps

Compound (8) (ie., the mixture of said α- and β-anomers above) is brominated in a conventional manner in solution of hydrogen bromide in acetic acid, to give 3-O-acetyl-2,4,6-trideoxy-2-fluoro-4-(trifluoroacetylamino)-α-L-mannopyranosyl bromide [Compound (9)] of the following formula ##STR16## as a 1-bromo-sugar. By the way, the corresponding 1-iodo-sugar can be obtained by reacting Compound (8) with iodo-trimethylsilane in anhydrous toluene.

Provenance & Evidence