HCID 18781569, compound → HCID 18781570, compound

Participants

Reaction Conditions

Reaction Steps

In a nitrogen atmosphere, 4.16 g (8.81 mmol) of 1-(diphenylphosphinyl)-2-iodo-3-trifluoromethyl benzene was dissolved in 40 ml of dimethyl formamide, and 1.5 g of copper powder was added and stirred for 30 minutes at 100° C. After allowing to cool, dimethyl formamide was distilled away in vacuo, and the residue was refined by chromatography (SiO2 70 g, CHCl3). By recrystallizing with ethyl acetate, 0.64 g (21%) of the captioned compound in the form of a white crystal was obtained.

Provenance & Evidence