Acetone → Cyclohexanol

HRID 1421410Notes

Reaction equation

HRID 1421410 reaction equation
[CH2:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:7][C:8]([CH3:10])=[O:9].[H][H].O=O>C(O)(=O)C>[CH:1]1([OH:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:8]1(=[O:9])[CH2:10][CH2:6][CH2:1][CH2:2][CH2:7]1

Participants

7

Reactant 4

HCID 180AcetoneHCID 977OxygenHCID 8078CyclohexaneHCID 178418361HCID 178418361, compound

Product 2

HCID 7966CyclohexanolHCID 7967Cyclohexanone

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

After adding cyclohexane (5 g), acetone (17 ml) and acetic acid (3 ml) to Pd/Fe2O3 (1 g), which was prepared by the same manner in Example 11, it was stirred at 30° C. for 48 hours in a flow of hydrogen and oxygen gases at the respective rate of 20 ml/min., filtered and dried for 24 hours in oven of 120° C. in order to activate the catalyst. To the activated catalyst (1 g), cyclohexane (5 g), acetone(17 ml) and acetic acid (3 ml) were added and stirred in a flow of hydrogen and oxygen gases at the respective rate of 20 ml/min. As the result of reaction for 16 hours at 30° C. under atmospheric pressure, 4.25 mole % of cyclohexanol and 7.25 mole % cyclohexanone with the total yield of 11.50 mole % were obtained.

Workup

  1. customwas prepared by the same manner in Example 11, it
  2. filtrationfiltered
  3. customdried for 24 hours in oven of 120° C. in order
  4. additionTo the activated catalyst (1 g), cyclohexane (5 g), acetone(17 ml) and acetic acid (3 ml) were added

Sources & evidence

ORD record
ord-ab996b49a10b44a1a2b03b8e5a833aa1
Source dataset
uspto-grants-2000_06
Patent number
US06075170

Reaction notes

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