HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazinecarboxylic acid, ethyl ester → 4-Chloro-4'-methylmercaptomethylbenzophenone ethoxycarbonylhydrazone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazinecarboxylic acid, ethyl ester | HCID 20064 | — |
| Reactant | 4-Chloro-4'-methylthiomethylbenzophenone | HCID 19689365 | — |
| Catalyst | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Chloro-4'-methylmercaptomethylbenzophenone ethoxycarbonylhydrazone | HCID 53972925 | 86.4% |
Reaction Steps
An ethanol solution (100 ml) of 4-chloro-4'-methylmercaptomethylbenzophenone (8.3 g), ethyl carbazate (10 g) and pyridinium p-toluenesulfonate (0.1 g) was heated for 16 hours with refluxing. After cooling to a room temperature, the reaction mixture was poured into ice water, and then the precipitated crystals were collected by filtration, and washed with water. After air-drying, 4-chloro-4'-methylmercaptomethylbenzophenone ethoxycarbonylhydrazone (9.4 g) was obtained as an isomer mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06077866 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-26a8f36fbe80426e8e59c2e85d55cee4 |
| Source note | uspto-grants-2000_06 |