Acetone → CID 11066066

HRID 1421665Notes

Reaction equation

HRID 1421665 reaction equation
CC(C)=O.[CH2:5]([O:7][C:8](=[O:13])[CH2:9][C:10]([O-:12])=[O:11])[CH3:6].[K+].[Cl-].[Mg+2:16].[Cl-].C([O-])(=O)CC([O-])=O>C(Cl)Cl>[Mg+2:16].[CH2:5]([O:7][C:8](=[O:13])[CH2:9][C:10]([O-:12])=[O:11])[CH3:6].[C:8]([O:7][CH2:5][CH3:6])(=[O:13])[CH2:9][C:10]([O-:12])=[O:11]

Participants

6

Reactant 4

HCID 180Acetone2×HCID 9084Malonate IonHCID 3446434Potassium ethyl malonateHCID 5360315Magnesium Chloride2×

Product 1

HCID 11066066CID 11066066

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A slurry of malonate monoethyl ester magnesium salt is prepared by adding an acetone slurry of potassium malonate monoethyl ester (144 g, 846 mmoles in 350 ml of acetone) to a slurry of magnesium chloride (72 g, 756 mmoles) which has been prepared by the slow addition of acetone (250 ml) to a slurry of magnesium chloride in methylene chloride (100 ml.) The malonate salt preparation is completed by atmospheric distillation to a volume of 350 ml.

Workup

  1. distillationis completed by atmospheric distillation to a volume of 350 ml

Sources & evidence

ORD record
ord-04b997ea2ac64909bd00ce2b0ceefab2
Source dataset
uspto-grants-2000_06
Patent number
US06077963

Reaction notes

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