Methanol → tert-butyl N-[4-(3,5-difluorophenyl)-3-[[3-[1-(4-fluorophenyl)ethylcarbamoyl]-5-(1-hydroxyethyl)benzoyl]amino]-2-hydroxybutyl]-N-[(3-methoxyphenyl)methyl]carbamate
Reaction equation
[BH4-:55].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH2:8][c:9]1[cH:10][c:11]([O:15][CH3:16])[cH:12][cH:13][cH:14]1)[CH2:17][CH:18]([CH:19]([CH2:20][c:21]1[cH:22][c:23]([F:28])[cH:24][c:25]([F:27])[cH:26]1)[NH:29][C:30]([c:31]1[cH:32][c:33]([C:49]([CH3:50])=[O:51])[cH:34][c:35]([C:37]([NH:38][CH:39]([CH3:40])[c:41]2[cH:42][cH:43][c:44]([F:47])[cH:45][cH:46]2)=[O:48])[cH:36]1)=[O:52])[OH:53])=[O:54].[CH3:57][OH:58].[Na+:56]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH2:8][c:9]1[cH:10][c:11]([O:15][CH3:16])[cH:12][cH:13][cH:14]1)[CH2:17][CH:18]([CH:19]([CH2:20][c:21]1[cH:22][c:23]([F:28])[cH:24][c:25]([F:27])[cH:26]1)[NH:29][C:30]([c:31]1[cH:32][c:33]([CH:49]([CH3:50])[OH:51])[cH:34][c:35]([C:37]([NH:38][CH:39]([CH3:40])[c:41]2[cH:42][cH:43][c:44]([F:47])[cH:45][cH:46]2)=[O:48])[cH:36]1)=[O:52])[OH:53])=[O:54]Participants
5
Sources & evidence
- ORD record
- ord-c8660ab5f94c4e3c9c95abc5fa639308
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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