HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 10513599, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 5-Methoxy-2-tetralone | HCID 259194 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 10513599 | HCID 10513599 | 99,399.797% |
Reaction Steps
A mixture of 5-methoxy-2-tetralone (100 g, 0.68 mmol), pyrrolidine (85.7 ml, 1.03 mol) and p-toluenesulfonic acid (100 mg, catalytic) in benzene (1.2L) was heated at reflux under Dean-Stark conditions for 4 h. The mixture was cooled and the solvent evaporated to give the title compound as a brown oil (155 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06080752 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-384934840d324b6fa0135c116961a7bf |
| Source note | uspto-grants-2000_06 |