HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 178526817, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 2-Bromo-5-nitrothiazole | HCID 18211 | — |
| Reactant | 3-(4-chlorophenyl)-1H-1,2,4-triazol-5-amine | HCID 691412 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178526817 | HCID 178526817 | — |
Reaction Steps
The title compound was prepared in a similar manner described in Example 1 by heating 3-amino-5-(4-chlorophenyl)-1,2,4-triazole with 2-bromo-5-nitrothiazole in refluxing tetrahydrofuran followed by silica gel column chromatograph by a solvent mixture of dichloromethane and methanol to yield 3-(4-chlorophenyl)-5-[(5-nitrothiazol-2-yl)amino]-1,2,4-triazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06080772 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-236e06e72a8649d0a7729fa6341b10aa |
| Source note | uspto-grants-2000_06 |