Methanol → Tert-butyl 3-(aminooxy)pyrrolidine-1-carboxylate

HRID 142206Notes

Reaction equation

HRID 142206 reaction equation
[CH3:25][NH:26][NH2:27].[CH3:31][OH:32].[Cl:28][CH2:29][Cl:30].[O:1]=[C:2]1[N:3]([O:12][CH:13]2[CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]2)[C:10](=[O:11])[c:5]2[c:4]1[cH:9][cH:8][cH:7][cH:6]2>>[NH2:3][O:12][CH:13]1[CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6061MethylhydrazineHCID 6344DichloromethaneHCID 19691445tert-butyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]pyrrolidine-1-carboxylate

Product 1

HCID 19691331Tert-butyl 3-(aminooxy)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-1814d8452705433892ed9bb025ef83fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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