5-(3-Fluorophenyl)-1,3-oxazole-4-carboxylic acid → 5-(3-Fluoro-phenyl)-oxazole-4-carboxylic Acid {2-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-yl}-amide

HRID 142207Notes

Reaction equation

HRID 142207 reaction equation
[F:17][c:18]1[cH:19][c:20](-[c:24]2[c:25]([C:29](=[O:30])[OH:31])[n:26][cH:27][o:28]2)[cH:21][cH:22][cH:23]1.[F:1][C:2]([CH3:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:10][n:11]2[n:12][cH:13][c:14]([NH2:16])[n:15]2)[o:9]1>>[F:1][C:2]([CH3:3])([F:4])[c:5]1[cH:6][cH:7][c:8]([CH2:10][n:11]2[n:12][cH:13][c:14]([NH:16][C:29]([c:25]3[c:24](-[c:20]4[cH:19][c:18]([F:17])[cH:23][cH:22][cH:21]4)[o:28][cH:27][n:26]3)=[O:30])[n:15]2)[o:9]1

Participants

3

Reactant 2

HCID 545955635-(3-Fluorophenyl)-1,3-oxazole-4-carboxylic acidHCID 67127834HCID 67127834, compound

Product 1

HCID 498345995-(3-Fluoro-phenyl)-oxazole-4-carboxylic Acid {2-[5-(1,1-difluoro-ethyl)-furan-2-ylmethyl]-2H-[1,2,3]triazol-4-yl}-amide

Sources & evidence

ORD record
ord-63df39fc078c46e5a33e5e53517d24d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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