Butyn-2-one → HCID 18706958, compound

Participants

Reaction Steps

1-Ethyl-8-benzyloxy-2-(4-benzyloxyphenyl)indolizine was reacted with 3-butyn-2-one by the general synthetic principles outlined in example 73, step 1, to afford the title compound as yellow crystals in 14% yield. M.p. 147-149° C. MS(SP): m/z 499 (M+). 1H--NMR (DMSO-d6, 200 MHz) δ: 1.37 (t, 3 H); 2.65 (s, 3 H); 3.16 (q, 2 H); 5.22 (s, 2 H); 5.53 (s, 2 H); 7.23 (d, 2 H); 7.33-7.83 (m, 13 H); 8.13 (s, 1 H); 8.28 (d, 1 H).

Provenance & Evidence