Acetic Anhydride → HCID 56622940, compound

Participants

Reaction Steps

The general synthetic pathway outlined in example 81, step 5, and example 83 have been applied to proper starting materials in the preparation of 3-(4-benzyloxyphenyl)-5-hydroxymethylpyrrolo[2,1,5-cd]indolizine-1,2-dicarboxylic acid, which was reacted with acetic acid anhydride by the general synthetic principles outlined in example 23, step 8, to afford 5-acetoxymethyl-3-(4-benzyloxyphenyl)pyrrolo[2,1,5-cd]indolizine-1,2-dicarboxylic acid anhydride as red crystals in 86%. 1H-NMR (DMSO-d6, 300 MHz) δ: 2.17 (s, 3H); 5.22 (s, 2H); 5.67 (s, 2H); 7.19 (d, 2H); 7.32-7.48 (m, 3H); 7.52 (d, 2H); 8.10-8.19 (m, 2H); 8.27 (d, 2H); 8.34 (d, 1H).

Provenance & Evidence