Sodium Hydroxide → HCID 57272556, compound

HRID 1422183Notes

Reaction equation

HRID 1422183 reaction equation
[OH:1][N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([O:10][CH2:11][CH:12]2[O:14][CH2:13]2)[CH2:4][C:3]1([CH3:16])[CH3:15].[OH-:17].[Na+]>>[OH:1][N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([O:10][CH2:11][CH:12]([OH:14])[CH2:13][OH:17])[CH2:4][C:3]1([CH3:16])[CH3:15]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 3662321HCID 3662321, compound

Product 1

HCID 57272556HCID 57272556, compound

Procedure

1.0 g of the compound of Example 3 is heated at 110° C. in 50 mL of 5% aqueous sodium hydroxide for six hours. The mixture is extracted with ethyl acetate, and the organic extract is dried and concentrated. The title compound is isolated as a red oil after column chromatography.

Workup

  1. extractionThe mixture is extracted with ethyl acetate
  2. extractionthe organic extract
  3. customis dried
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-f457ae05d8544260a0ea85ba208c896f
Source dataset
uspto-grants-2000_06
Patent number
US06080864

Reaction notes

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