p-Cyanobenzyl alcohol → HCID 18779156, compound

HRID 1422343Notes

Reaction equation

HRID 1422343 reaction equation
[C:1]([C:3]1[CH:10]=[CH:9][C:6]([CH2:7]O)=[CH:5][CH:4]=1)#[N:2].[Br:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][C:19]2[N:20]=[CH:21][N:22](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[CH:23]=2)=[CH:14][CH:13]=1>>[Br:11][C:12]1[CH:13]=[CH:14][C:15]([O:18][C:19]2[N:20]([CH2:7][C:6]3[CH:9]=[CH:10][C:3]([C:1]#[N:2])=[CH:4][CH:5]=3)[CH:21]=[N:22][CH:23]=2)=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 160549p-Cyanobenzyl alcoholHCID 18698776HCID 18698776, compound

Product 1

HCID 18779156HCID 18779156, compound

Procedure

The title compound was prepared as a white solid using the protocol described in example 5, step C using, 4-cyanobenzyl alcohol and 4-(4-bromophenyloxy)-1-trityl-imidazole. The title compound was purified by chromatography (Silica gel 3:7 acetone in CHCl3).

Workup

  1. customThe title compound was purified by chromatography (Silica gel 3:7 acetone in CHCl3)

Sources & evidence

ORD record
ord-433c4c9439d54b4ba225e13b68ec0412
Source dataset
uspto-grants-2000_06
Patent number
US06080870

Reaction notes

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