HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon tetrabromide → HCID 53770216, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon tetrabromide | HCID 11205 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | (3',5'-Dichloro[1,1'-biphenyl]-4-yl)methanol | HCID 11288229 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 53770216 | HCID 53770216 | — |
Reaction Steps
To a solution of triphenylphospine (636 mg, 2.42 mmol) and carbon tetrabromide (830 mg, 2.50 mmol) in diethyl ether (5 mL) was added a solution of 4-(3',5'-bis-chlorophenyl) benzyl alcohol (50 mg, 1.98 mmol) in CH2Cl2 (12 mL). The reaction was stirred at ambient temperature for 16 hours, silica gel was than added and the solvent evaporated in vacuo. The product was isolated by chromatography (Silica gel, 10-30% EtOAc in hexanes) and obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06080870 |
| Source dataset | uspto-grants-2000_06 |
| ORD ID | ord-bad8f4f388c7478aa18d0c8d52b766e7 |
| Source note | uspto-grants-2000_06 |