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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1422372Generated: October 31, 2026

(1-Chloroethyl)benzene → (E,5S)-5-phenylhex-3-en-1-ol

https://huagongshe.com/reaction/1422372

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1-Chloroethyl)benzeneHCID 12648—
Reactant(3E)-4-bromobut-3-en-1-olHCID 14740944—
ReagentSodium IodideHCID 5238—
Catalyst(3aR,3a'R,8aS,8a'S)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)HCID 11245230—
CatalystDichloronickel;1,2-dimethoxyethaneHCID 15773433—
SolventDimethylacetamideHCID 31374—
Product(E,5S)-5-phenylhex-3-en-1-olHCID 16240240256%

Reaction Conditions

Temperature0 °C

Provenance & Evidence

DOI10.1021/acscatal.9b01785
Source datasetElectroreductive Coupling of Alkenyl and Benzyl Halides
ORD IDord-a1674a7659ec4286a3ba520bab2e5c74
Source noteElectroreductive Coupling of Alkenyl and Benzyl Halides