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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1422413Generated: October 29, 2026

4-Bromo-3,5-dimethyl-1,2-oxazole → 2-Chloro-4-(3,5-dimethyl-isoxazol-4-yl)-pyridine

https://huagongshe.com/reaction/1422413

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-3,5-dimethyl-1,2-oxazoleHCID 318421—
Reactant2-Chloro-4-[1-(tetrahydro-pyran-2-yl)-1H-pyrazol-4-yl]-pyridineHCID 59534355—
Product2-Chloro-4-(3,5-dimethyl-isoxazol-4-yl)-pyridineHCID 59534449—

Reaction Steps

The title compound was prepared from 4-bromo-3,5-dimethylisoxazole generally according to the synthetic procedure described for 2-Chloro-4-[1-(tetrahydro-pyran-2-yl)-1H-pyrazol-4-yl]-pyridine. HPLC (Rt)=0.81 min (method N)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE045323E1
Source datasetuspto-grants-2015_01
ORD IDord-c0508a5dcc9945de9147310e74c962ad
Source noteuspto-grants-2015_01