1-(2-Amino-3-chloro-4-methoxyphenyl)ethanone → HCID 58289536, compound

HRID 1422539Notes

Reaction equation

HRID 1422539 reaction equation
[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([Cl:17])[C:8]([O:12][CH2:13]COC)=[CH:9][CH:10]=2)[N:5]=[C:4]([C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]([CH3:26])[CH3:25])[N:19]=2)[CH:3]=1.NC1C(Cl)=C(OC)C=CC=1C(=O)C>>[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([Cl:17])[C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[C:4]([C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]([CH3:26])[CH3:25])[N:19]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 299199881-(2-Amino-3-chloro-4-methoxyphenyl)ethanoneHCID 58289568HCID 58289568, compound

Product 1

HCID 58289536HCID 58289536, compound

Procedure

4,8-Dichloro-2-(6-isopropyl-pyridin-2-yl)-7-methoxy-quinoline was prepared in a similar fashion as 4,8-dichloro-2-(6-isopropyl-pyridin-2-yl)-7-(2-methoxy-ethoxy)-quinoline except that 1-(2-amino-3-chloro-4-methoxy-phenyl)-ethanone was used instead of 1-[2-amino-3-chloro-4-(2-methoxy-ethoxy)-phenyl]-ethanone.

Sources & evidence

ORD record
ord-fbb896d55f7f4e64b8413adf247db305
Source dataset
uspto-grants-2015_01
Patent number
US08927484B2

Reaction notes

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