Pyridine → HCID 67083599, compound

Participants

Reaction Conditions

Reaction Steps

4-O-benzyl-D-glucal (21.2 mmol) and pyridine (45 mmol), were dissolved in dichloromethane (100 mL). Obtained solution was cooled down to 0° C., and acetyl chloride (25 mmol) was added. The mixture was stirred at 0° C. After reaction was completed, the reaction mixture was washed with water (3×50 mL), dried over anhydrous sodium sulfate. Drying agent and solvent were removed and product was purified by column chromatography (Silicagel 60) using hexanes:ethyl acetate as eluents. Yield 50%.

Provenance & Evidence