HuagongsheHuagongshe Chemistry Print Report · For research reference only
{(S)-6-[(R)-4-bromo-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester → HCID 90313717, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | {(S)-6-[(R)-4-bromo-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester | HCID 86700774 | — |
| Reactant | (1-Oxa-8-azonia-spiro[4.5]dec-8-yl)methyltrifluoroborate | HCID 90313784 | — |
| Product | HCID 90313717 | HCID 90313717 | — |
Reaction Steps
The title compound is prepared from {(S)-6-[(R)-4-bromo-5-trifluoromethyl-indan-1-yloxy]-2,3-dihydro-benzofuran-3-yl}-acetic acid methyl ester and (1-oxa-8-azonia-spiro[4.5]dec-8-yl)methyltrifluoroborate following a procedure analogous to that described for Intermediate 3. LC (method 1): tR=0.93 min; Mass spectrum (ESI+): m/z=546 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927531B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-2c5a3337db904e7bbefbe57abdd1718c |
| Source note | uspto-grants-2015_01 |