HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → Bis-benzyloxy benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | Methyl 2,3-bis(benzyloxy)benzoate | HCID 10665397 | — |
| Product | Bis-benzyloxy benzoic acid | HCID 10520703 | — |
Reaction Steps
In another embodiment the compounds can be prepared as shown in Scheme III. A nitroaniline (1) can be reacted with propionyl chloride to yield nitro-phenyl-propionamide (2). NaH can then be added to a solution of (2) in anhydrous THF followed by iodomethane to give pure product nitro-phenyl-N-methyl-propionamide (3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927548B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-c476a50e3ae1452aa08bb1411ed5b4c9 |
| Source note | uspto-grants-2015_01 |