HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxy-5-nitroindane → 5-amino-2,3-dihydro-1H-inden-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxy-5-nitroindane | HCID 3685927 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | 5-amino-2,3-dihydro-1H-inden-2-ol | HCID 21555031 | — |
Reaction Steps
5-nitro-indan-2-ol (450 mg, 2.5 mmol) was hydrogenated using Pd/C (10%, dry, 100 mg) and H2 balloon at 1 atm at room temperature. Pd/C was filtered off through a pad of celite and the mother liquid was concentrated to give the crude product, 5-Amino-indan-2-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927548B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-960efe60fb0a423c8648676886e9ecd2 |
| Source note | uspto-grants-2015_01 |