3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid → 3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid [6-(6-methoxy-4-methyl-3,4-dihydro-2H-1-oxa-4,5,9-triaza-phenanthren-3-yl)-pyridin-3-yl]-amide

Participants

Role	Name	HCID	Charge
Reactant	3-oxo-3,4-dihydro-2H-1,4-benzothiazine-6-carboxylic acid	HCID 760993	—
Reactant	[6-(6-methoxy-4-methyl-3,4-dihydro-2H-1-oxa-4,5,9-triaza-phenanthren-3-yl)-pyridin-3-yl]-carbamic acid tert-butyl ester	HCID 67247488	—
Product	3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid [6-(6-methoxy-4-methyl-3,4-dihydro-2H-1-oxa-4,5,9-triaza-phenanthren-3-yl)-pyridin-3-yl]-amide	HCID 86671534	—

Reaction Steps

The titled compound is prepared as a light yellow lyophilizated powder following Scheme 5 and in analogy to Example 1 using [6-(6-methoxy-4-methyl-3,4-dihydro-2H-1-oxa-4,5,9-triaza-phenanthren-3-yl)-pyridin-3-yl]-carbamic acid tert-butyl ester and 3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-6-carboxylic acid acid as starting materials.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08927541B2
Source dataset	uspto-grants-2015_01
ORD ID	ord-8c16e4b9e87e4f918a93fbe95832876e
Source note	uspto-grants-2015_01