(6-Bromopyridin-2-yl)(4-fluorophenyl)methanol → HCID 86672833, compound

Participants

Reaction Steps

To a chilled (0° C.) solution of (6-bromopyridin-2-yl)-(4-fluorophenyl)-methanol (6.2 g, 22 mmol) in dichloromethane (88 mL) is added pyridinium chlorochromate (PCC) (7.1 g, 33 mmol). The reaction mixture is allowed to warm to room temperature. After 5 hours, the reaction mixture is concentrated and purified by silica gel chromatography eluting with 10% EtOAc in hexanes to afford (6-bromopyridin-2-yl)-(4-fluorophenyl)-methanone.

Provenance & Evidence