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HRID1423154

反应详情

EQUATION

反应方程式

HRID 1423154 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)CC(=O)Cl
HCID118931

Ethyl 3-chloro-3-oxopropionate

C5H7ClO3

结构：COc1ccc(N2CCN[C@@H](Cc3ccccc3)C2)cc1OC1CCC1
HCID58188985

未命名化合物

2 次

PRODUCTS

生成物

1
结构：COc1ccc(N2CCN(C(=O)CC(=O)O)[C@@H](Cc3ccccc3)C2)cc1OC1CCC1
HCID66828643

未命名化合物

PROCEDURE

实验过程

Prepared by the method outlined for Example 127 using chlorocarbonyl-acetic acid ethyl ester and 3(S)-benzyl-1-(3-cyclobutoxy-4-methoxy-phenyl)-piperazine (Example 7, Compound 95) as starting material. Product as an oil (25 mg, 65%). LC/MS (Method B) 2.56 min, [M+1]+ 439. Potency class A.

WORKUP

后处理

  1. customPrepared by the method
  2. customLC/MS (Method B) 2.56 min, [M+1]+ 439