HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58189029, compound → (S)-1-(2-benzyl-4-(3-isopropoxy-4-methoxyphenyl)piperazin-1-yl)-2-(5-nitro-1H-1,2,4-triazol-3-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58189029 | HCID 58189029 | — |
| Reactant | 2-(5-Nitro-1H-1,2,4-triazol-3-yl)acetic acid | HCID 135430111 | — |
| Product | (S)-1-(2-benzyl-4-(3-isopropoxy-4-methoxyphenyl)piperazin-1-yl)-2-(5-nitro-1H-1,2,4-triazol-3-yl)ethanone | HCID 135988895 | — |
Reaction Steps
Prepared by the method outlined for Example 189 using (5-Nitro-1H-[1,2,4]triazol-3-yl)-acetic acid and 3 (S)-benzyl-1-(3-(1-methylethoxy)-4-methoxy-phenyl)-piperazine (Example 9, Compound 97) as starting materials. Product as an oil. LC/MS (Method B) 3.10 min, [M+1]+ 495. Potency class C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927546B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-6be7950e5cfc4759be6661f9e16da509 |
| Source note | uspto-grants-2015_01 |