HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58188985, compound → (S)-1-(2-benzyl-4-(3-cyclobutoxy-4-methoxyphenyl)piperazin-1-yl)-2-(5-nitro-1H-1,2,4-triazol-3-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58188985 | HCID 58188985 | — |
| Reactant | 2-(5-Nitro-1H-1,2,4-triazol-3-yl)acetic acid | HCID 135430111 | — |
| Product | (S)-1-(2-benzyl-4-(3-cyclobutoxy-4-methoxyphenyl)piperazin-1-yl)-2-(5-nitro-1H-1,2,4-triazol-3-yl)ethanone | HCID 135988894 | — |
Reaction Steps
Prepared by the method outlined for Example 189 using (5-Nitro-1H-[1,2,4]triazol-3-yl)-acetic acid and 3(S)-benzyl-1-(3-cyclobutoxy-4-methoxy-phenyl)-piperazine (Example 7, Compound 95) as starting materials to afford product as an oil. LC/MS (Method B) 3.18 min, [M+1]+ 507. Potency class B.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927546B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-828c43b0a3e84038b65775f6aa778157 |
| Source note | uspto-grants-2015_01 |