HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridineacetic acid → (S)-1-(2-benzyl-4-(1-cyclobutyl-3-ethyl-1H-indazol-6-yl)piperazin-1-yl)-2-(pyridin-2-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridineacetic acid | HCID 85318 | — |
| Reactant | HCID 23627567 | HCID 23627567 | — |
| Product | (S)-1-(2-benzyl-4-(1-cyclobutyl-3-ethyl-1H-indazol-6-yl)piperazin-1-yl)-2-(pyridin-2-yl)ethanone | HCID 58189035 | — |
Reaction Steps
Prepared by the method outlined for Example 189 using pyridine-2-yl-acetic acid and 6-((S)3-benzyl-piperazin-1-yl)-1-cyclobutyl-3-ethyl-1H-indazole (Example 56, Compound 144) as starting materials. Product as an oil (30 mg, 68%). LC/MS (Method B) 2.76 min, [M+1]+ 494. Potency class C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927546B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-be64ce28b7264aafa1d890b0e51a3086 |
| Source note | uspto-grants-2015_01 |