HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23627567, compound → (S)-1-(2-benzyl-4-(1-cyclobutyl-3-ethyl-1H-indazol-6-yl)piperazin-1-yl)-2-(5-nitro-1H-1,2,4-triazol-3-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23627567 | HCID 23627567 | — |
| Reactant | 2-(5-Nitro-1H-1,2,4-triazol-3-yl)acetic acid | HCID 135430111 | — |
| Product | (S)-1-(2-benzyl-4-(1-cyclobutyl-3-ethyl-1H-indazol-6-yl)piperazin-1-yl)-2-(5-nitro-1H-1,2,4-triazol-3-yl)ethanone | HCID 135988891 | — |
Reaction Steps
Prepared by the method outlined for Example 189 using (5-Nitro-1H-[1,2,4]triazol-3-yl)-acetic acid and ester 6-(S)-3-benzyl-piperazin-1-yl)-1-cyclobutyl-3-ethyl-1H-indazole (Example 56, Compound 144) as starting materials. Product as an oil. LC/MS (Method B) 2.56 min, [M+1]+ 529. Potency class ND.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927546B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-00d76fd4ba784207a4d3956f8cc8bc3a |
| Source note | uspto-grants-2015_01 |