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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423181Generated: November 3, 2026

2-Pyrimidineacetic Acid → HCID 58189017, compound

https://huagongshe.com/reaction/1423181

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrimidineacetic AcidHCID 12367098—
ReactantHCID 58189227HCID 58189227—
ProductHCID 58189017HCID 58189017—

Reaction Steps

Prepared by the method outlined for Example 189 using pyrimidin-2-yl-acetic acid and (S)-3-benzyl-1-(3-cyclobutoxy-4-difluoromethoxy-phenyl)-piperazine (Example 4, Compound 92) as starting materials. Product as an oil. LC/MS (Method B) 2.86 min, [M+1]+ 509. Potency class B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927546B2
Source datasetuspto-grants-2015_01
ORD IDord-e48941da3a83405ba06a757c8e29555e
Source noteuspto-grants-2015_01