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HRID1423182

反应详情

EQUATION

反应方程式

HRID 1423182 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)Cc1ncccn1
HCID12367098

(Pyrimidin-2-yl)acetic acid

C6H6N2O2

结构：COc1ccc(N2CCN[C@@H](Cc3ccccc3)C2)cc1OC(F)F
HCID52920372

未命名化合物

2 次

PRODUCTS

生成物

1
结构：COc1ccc(N2CCN(C(=O)Cc3ncccn3)[C@@H](Cc3ccccc3)C2)cc1OC(F)F
HCID58189102

未命名化合物

PROCEDURE

实验过程

Prepared by the method outlined for Example 189 using pyrimidin-2-yl-acetic acid and (S)-3-benzyl-1-(3-difluoromethoxy-4-methoxy-phenyl)-piperazine (Example 69, Compound 157) as starting materials. Product as an oil. LC/MS (Method B) 2.46 min, [M+1]+ 468. Potency class ND.

WORKUP

后处理

  1. customPrepared by the method
  2. customLC/MS (Method B) 2.46 min, [M+1]+ 468