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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423187Generated: November 2, 2026

Imidazole-4-acetic acid → HCID 178445827, compound

https://huagongshe.com/reaction/1423187

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazole-4-acetic acidHCID 96215—
ReactantHCID 52920368HCID 52920368—
ProductHCID 178445827HCID 178445827—

Reaction Steps

Prepared by the method outlined for Example 189 using 2-(1H-imidazol-4-yl)acetic acid and (S)-1-(3-cyclopentyloxy-4-difluoromethoxy-phenyl)-3-isobutyl-piperazine (Example 36, Compound 124) as starting materials. Product as an off-white solid (20%). LC/MS (Method B) 3.04 min, [M+1]+ 477.1. Potency class B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927546B2
Source datasetuspto-grants-2015_01
ORD IDord-535bfdcfa05449e49dc32bfad59bcc85
Source noteuspto-grants-2015_01