HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole-4-acetic acid → HCID 178491982, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole-4-acetic acid | HCID 96215 | — |
| Reactant | (S)-1-(3-cyclobutlyoxy-4-methoxy-phenyl)-3-isobutyl-piperazine | HCID 58188990 | — |
| Product | HCID 178491982 | HCID 178491982 | — |
Reaction Steps
Prepared by the method outlined for Example 189 using 2-(1H-imidazol-4-yl)acetic acid and (S)-1-(3-cyclobutlyoxy-4-methoxy-phenyl)-3-isobutyl-piperazine (Example 34, Compound 122) as starting materials. Product as a light brown solid (17%). LC/MS (Method B) 2.57 min, [M+1]+ 427.0. Potency class A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927546B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-c5b70c3ef5c0438e8dd5782c1d60fc90 |
| Source note | uspto-grants-2015_01 |