HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxazole-5-acetic Acid → (S)-1-(2-benzyl-4-(3-ethyl-1-isopropyl-1H-indazol-6-yl)piperazin-1-yl)-2-(oxazol-5-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxazole-5-acetic Acid | HCID 21197975 | — |
| Reactant | 6-((S)-3-benzyl-piperazin-1-yl)-1-isopropyl-3-ethyl-1H-indazole | HCID 58189246 | — |
| Product | (S)-1-(2-benzyl-4-(3-ethyl-1-isopropyl-1H-indazol-6-yl)piperazin-1-yl)-2-(oxazol-5-yl)ethanone | HCID 58189067 | 34% |
Reaction Steps
Prepared by the method outlined for Example 189 using 2-(oxazol-5-yl)acetic acid and 6-((S)-3-benzyl-piperazin-1-yl)-1-isopropyl-3-ethyl-1H-indazole as starting materials. Product was obtained as a light brown solid (34%). LC/MS (Method B) 3.77 min, [M+1]+ 472.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927546B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-affb7444e9194b7aad984571991bf71c |
| Source note | uspto-grants-2015_01 |