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HRID1423203

反应详情

EQUATION

反应方程式

HRID 1423203 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)Cc1ncccn1
HCID12367098

(Pyrimidin-2-yl)acetic acid

C6H6N2O2

结构：COc1ccc(N2CCN[C@@H](Cc3ccc(F)cc3)C2)cc1OC1CCC1
HCID58189210

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(N2CCN(C(=O)Cc3ncccn3)[C@@H](Cc3ccc(F)cc3)C2)cc1OC1CCC1
HCID58189061

未命名化合物

收率 81%

PROCEDURE

实验过程

Prepared by the method outlined for Example 189 using (S)-1-(3-cyclobutoxy-4-methoxyphenyl)-3-(4-fluorobenzyl)piperazine and 2-(pyrimidin-2-yl)acetic acid as starting materials. Product was obtained as a colorless solid (81%). LC/MS 3.59 min, [M+1]+ 491.

WORKUP

后处理

  1. customPrepared by the method