HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58188985, compound → (S)-1-(2-benzyl-4-(3-cyclobutoxy-4-methoxyphenyl)piperazin-1-yl)-2-(1H-pyrazol-4-yl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58188985 | HCID 58188985 | — |
| Reactant | methyl 2-(1H-pyrazol-4-yl)acetate | HCID 58189211 | — |
| Product | (S)-1-(2-benzyl-4-(3-cyclobutoxy-4-methoxyphenyl)piperazin-1-yl)-2-(1H-pyrazol-4-yl)ethanone | HCID 58189175 | 14% |
Reaction Steps
Prepared using the same procedure described in Example 275 from (S)-3-benzyl-1-(3-cyclobutyloxy-4-methoxy-phenyl)-piperazine and (1H-pyrazol-4-yl)-acetic acid methyl ester with heating for 17 days to afford the title compound as an off-white solid (20 mg, 14%). LC/MS (Method B) 3.42 min, [M+1]+ 461.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08927546B2 |
| Source dataset | uspto-grants-2015_01 |
| ORD ID | ord-52c42896505442d298ee37d19a1f4ec1 |
| Source note | uspto-grants-2015_01 |