反应详情

Prepared using the same procedure described in Example 275 from (S)-3-benzyl-1-(3-cyclobutoxy-4-difluoromethoxy-phenyl)-piperazine and (4H-[1,2,4]triazol-3-yl)-acetic acid ethyl ester with heating for 15 days to afford the title compound as a yellow solid (87 mg, 32%). LC/MS (Method B) 3.64 min, [M+1]+ 498.

1. customPrepared
2. temperaturewith heating for 15 days