反应详情

Prepared using the same procedure described in Example 405 from 5-((S)-3-benzyl-piperazin-1-yl)-8-methoxy-2-trifluoromethyl-quinoline (254 mg, 0.63 mmol) and chloroacetone (60 μL), to afford the title compound as yellow solid (288 mg, 98%). LC/MS (Method B) 2.67 min, [M+1]+ 458.

1. customPrepared