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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423300Generated: November 2, 2026

Water → HCID 86615228, compound

https://huagongshe.com/reaction/1423300

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 54753949HCID 54753949—
SolventMethanolHCID 887—
ProductHCID 86615228HCID 8661522885.8%

Reaction Steps

A solution of (S)-4-tert-butoxycarbonylamino-2-hydroxybutyric acid methyl ester (1.52 g, 6.52 mmol) in methanol (20.0 mL) was treated with lithium hydroxide monohydrate (273.8 mg, 6.52 mmol) and water (2.0 mL) for 30 min, concentrated, and dried under vacuum to give a white solid (1.26 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927573B2
Source datasetuspto-grants-2015_01
ORD IDord-7eebd62163aa4d4da9718133e7395c8f
Source noteuspto-grants-2015_01