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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423392Generated: November 2, 2026

2-Bromo-5-fluorophenol → 1-Bromo-2-(cyclopropylmethoxy)-4-fluorobenzene

https://huagongshe.com/reaction/1423392

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-fluorophenolHCID 2724600—
Reactant1-Bromo-1-methylcyclopropaneHCID 14864946—
Product1-Bromo-2-(cyclopropylmethoxy)-4-fluorobenzeneHCID 66866945—

Reaction Steps

Starting from commercially available 2-bromo-5-fluoro-phenol and commercially available bromo-methyl-cyclopropane the title compound is obtained as colorless oil after distillation at 5×103 mbar.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927557B2
Source datasetuspto-grants-2015_01
ORD IDord-71462668f47544dcb4f7a746028d9a4f
Source noteuspto-grants-2015_01