2-Bromo-4-fluorophenol → 2-Bromo-1-(cyclopropylmethoxy)-4-fluorobenzene

HRID 1423393Notes

Reaction equation

HRID 1423393 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[OH:9].Br[C:11]1([CH3:14])[CH2:13][CH2:12]1>>[Br:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[O:9][CH2:14][CH:11]1[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 6054722-Bromo-4-fluorophenolHCID 148649461-Bromo-1-methylcyclopropane

Product 1

HCID 435603962-Bromo-1-(cyclopropylmethoxy)-4-fluorobenzene

Procedure

Starting from commercially available 2-bromo-4-fluoro-phenol and commercially available bromo-methyl-cyclopropane the title compound is obtained as colorless oil after distillation at 5×10−3 mbar.

Sources & evidence

ORD record
ord-73d838f6849a4e168e0d11c55440435a
Source dataset
uspto-grants-2015_01
Patent number
US08927557B2

Reaction notes

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