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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423421Generated: October 31, 2026

2-(2-(Cyclopropylmethoxy)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → Ethyl 4-(2-Cyclopropylmethoxy-5-fluoro-phenyl)-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate

https://huagongshe.com/reaction/1423421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-(Cyclopropylmethoxy)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 56923638—
ReactantHCID 86666646HCID 86666646—
ProductEthyl 4-(2-Cyclopropylmethoxy-5-fluoro-phenyl)-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylateHCID 67956096—

Reaction Steps

Starting from ethyl 4-chloro-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate (example A4) and 2-(2-cyclopropylmethoxy-5-fluoro-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (example B.c4) the title compound is obtained as off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927557B2
Source datasetuspto-grants-2015_01
ORD IDord-75155f4e6b2c4b4bac52facdca84bfd4
Source noteuspto-grants-2015_01