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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423455Generated: November 2, 2026

4-[2-(cyclopropylmethoxy)-4-fluorophenyl]-6-methyl-5-{[2-(trimethylsilyl)ethoxy]methyl}-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid → HCID 178429361, compound

https://huagongshe.com/reaction/1423455

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-(cyclopropylmethoxy)-4-fluorophenyl]-6-methyl-5-{[2-(trimethylsilyl)ethoxy]methyl}-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acidHCID 67956161—
ReactantHCID 178419079HCID 178419079—
ProductHCID 178429361HCID 178429361—

Reaction Steps

Starting from 4-[2-(cyclopropylmethoxy)-4-fluorophenyl]-6-methyl-5-{[2-(trimethylsilyl)ethoxy]methyl}-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example D.c2) and commercially available tert-butyl trans-(4-amino-cyclohexyl)-carbamate the title compound is obtained as pale yellow viscous oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927557B2
Source datasetuspto-grants-2015_01
ORD IDord-73a087f2224141da8a7827625b741f54
Source noteuspto-grants-2015_01