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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1423507Generated: October 25, 2026

4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid → HCID 178433585, compound

https://huagongshe.com/reaction/1423507

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acidHCID 67956012—
ReactantHCID 178419079HCID 178419079—
ProductHCID 178433585HCID 178433585—

Reaction Steps

Starting from 4-[2-(cyclopropylmethoxy)-5-(difluoromethyl)phenyl]-6-methyl-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid (example D.g1) and commercially available tert-butyl trans-(4-amino-cyclohexyl)-carbamate the title compound is obtained as pale yellow foam.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08927557B2
Source datasetuspto-grants-2015_01
ORD IDord-fa4de623499a4d9abfbb7b334b0b5dbc
Source noteuspto-grants-2015_01